Researchers at Osaka University are stepping up efforts to develop robotic body parts controlled by thought, by placing electrode sheets directly on the surface of the brain. Led by Osaka University Medical School neurosurgery professor Toshiki Yoshimine, the research marks Japan’s first foray into invasive (i.e. requiring open-skull surgery) brain-machine interface research on human test subjects. The aim of the research is to develop real-time mind-controlled robotic limbs for the disabled, according to an announcement made at an April 16 symposium in Aichi prefecture.
Although brain waves can be measured from outside the scalp, a stronger, more accurate signal can be obtained by placing sensors directly on the brain — but that requires open-skull surgery, making it more difficult to recruit volunteer test subjects.
The researchers, who have filed a license application with the Osaka University Hospital ethics board, are working to enlist willing subjects already scheduled to have brain electrodes implanted for the purpose of monitoring epilepsy or other conditions. The procedure, which does not involve puncturing the cortex, places an electrode sheet at the central sulcus, a fold across the center of the brain near the primary motor cortex (which is responsible for planning and executing movements).
To date, the researchers have worked with four test subjects to record brain wave activity generated as they move their arms, elbows and fingers. Working with Advanced Telecommunications Research Institute International (ATR), the researchers have developed a method for analyzing the brain waves to determine the subject’s intended activity to an accuracy of greater than 80%. The next step is to use the data to control robot arms developed by the University of Tokyo’s Department of Precision Engineering.
In an effort to accelerate the development of next-generation automobiles and robots, Toyota is turning to some of Japan’s top neuroscientists. According to a December 14 announcement, the automaker has teamed up with the Institute of Physical and Chemical Research (RIKEN) in a 20-year project aimed at researching the human brain and developing neurotechnology-based auto safety systems, sophisticated robots, and machinery that users can operate with their minds.
Toyota and RIKEN will conduct the brain research at the recently established RIKEN BSI-Toyota Collaboration Center, which will initially be staffed by 30 researchers, 5 of whom are from Toyota. The research will fall into three broad categories: (1) neuro-driving research, which focuses on the mental processes at work as drivers perceive, judge and react to the external environment, (2) neuro-robotics research, which focuses on how the brain processes information, and (3) mind-health research, which focuses on the physiology of the brain and nervous system and the relationship between the brain and physical health.
Through the neuro-driving research, which is expected to shed new light on how the brain works as drivers perceive obstacles and operate their vehicles, Toyota ultimately hopes to develop auto safety technology that can completely prevent all traffic accidents.
In addition, the automaker explains that the purpose behind the neuro-robotics research is to develop advanced robots that can interact more effectively with humans. Toyota, which sees robotics as one of its core businesses in the future, has been stepping up efforts in recent years to develop “lifestyle support” androids for use in nursing and health care. The company also believes the research will lead to the development of brain-machine interfaces that allow users to operate equipment by thought.
Toyota explains that the decision to pursue brain research is driven by an ever-increasing demand for more sophisticated automotive and robot technology. With a better understanding of the cognitive mechanisms underlying human feelings, thoughts and actions, the company reckons it can get a head start in the race to develop the cars and robots of the future.
A team of University of Tokyo researchers led by professors Hitoshi Sakano and Ko Kobayakawa have announced they have genetically engineered a mouse that does not fear cats, simply by controlling its sense of smell. By tweaking genes to disable certain functions of the olfactory bulb — the area of the brain that receives information about smells directly from olfactory receptors in the nose — the researchers were able to create a “fearless” mouse that does not try to flee when it smells cats, foxes and other predators.
In studying the genetically modified mouse, the researchers have concluded that the evasive behavior exhibited by mammals when they smell predators may be genetically hardwired into the olfactory bulb from birth, and not learned through experience as commonly believed. The research suggests that the mechanism by which mammals determine whether or not to fear another animal they smell — and whether or not to flee — is not a higher-order cerebral function. Instead, that decision is made based on a lower-order function that is hardwired into the neural circuitry of the olfactory bulb. However, in other experiments, the researchers demonstrated that mice with impaired olfactory functions can also be taught to fear their predators.
According to Professor Sakano, the research indicates that behavior in the mammalian brain is determined both by instincts coded into the genes and by “associative circuitry” that allows responses to be learned through the environment.
The results of the research, which are to be published in the November 8 online edition of the British science journal Nature, are expected to help scientists better understand the structure of the brain’s neural circuitry responsible for processing information about the outside world.
While recent developments in brain-computer interface (BCI) technology have given humans the power to mentally control computers, nobody has used the technology in conjunction with the Second Life online virtual world — until now.
A research team led by professor Jun’ichi Ushiba of the Keio University Biomedical Engineering Laboratory has developed a BCI system that lets the user walk an avatar through the streets of Second Life while relying solely on the power of thought. To control the avatar on screen, the user simply thinks about moving various body parts — the avatar walks forward when the user thinks about moving his/her own feet, and it turns right and left when the user imagines moving his/her right and left arms.
The system consists of a headpiece equipped with electrodes that monitor activity in three areas of the motor cortex (the region of the brain involved in controlling the movement of the arms and legs). An EEG machine reads and graphs the data and relays it to the BCI, where a brain wave analysis algorithm interprets the user’s imagined movements. A keyboard emulator then converts this data into a signal and relays it to Second Life, causing the on-screen avatar to move. In this way, the user can exercise real-time control over the avatar in the 3D virtual world without moving a muscle.
Future plans are to improve the BCI so that users can make Second Life avatars perform more complex movements and gestures. The researchers hope the mind-controlled avatar, which was created through a joint medical engineering project involving Keio’s Department of Rehabilitation Medicine and the Tsukigase Rehabilitation Center, will one day help people with serious physical impairments communicate and do business in Second Life.
Wake up and smell the pencil lead, says Japanese stationery and writing instrument manufacturer Pentel, who has combined the power of nanotechnology with the knowledge of expert aromatherapists to develop a new type of fragrant pencil lead. Featuring a long-lasting aroma designed to enhance mental capacity, the pencil lead — called “Ain supplio” — recently won the coveted Stationery of the Year Award (2007).
Unlike previous types of fragrant lead, which use weak aromatic surface coatings that tend to lose their smell quickly, Ain supplio relies on fragrant ingredients trapped in nanocapsules, or tiny air bubbles, which are infused into the lead itself. The microscopic size of the nanocapsules gives them extra strength to hold their fragrance for long periods of time — about 3 years if kept in the unopened package, 2 years if kept in their plastic case, and more than 3 months out in the open air.
Tentatively priced at 210 yen (under $2) per set, Ain supplio comes in three flavors — Refresh, Healing and Positive — each prepared by aromatherapists working with ingredients such as rosemary, mint, lemongrass and green tea. The aromatic blends are specially designed to boost the learning capacity of those in smelling range, says Pentel, who hopes the product will appeal to students. Ain supplio will hit shelves in September, just in time for the fall semester.
Hitachi has successfully trial manufactured a lightweight, portable brain scanner that enables users to keep tabs on their mental activity during the course of their daily lives. The system, which consists of a 400 gram (14 oz) headset and a 630 gram (1 lb 6 oz) controller worn on the waist, is the result of Hitachi’s efforts to transform the brain scanner into a familiar everyday item that anyone can use.
The rechargeable battery-operated mind reader relies on Hitachi’s so-called “optical topography” technology, which interprets mental activity based on subtle changes in the brain’s blood flow. Because blood flow increases to areas of the brain where neurons are firing (to supply glucose and oxygen to the tissue), changes in hemoglobin concentrations are an important index by which to measure brain activity. To measure these hemoglobin concentrations in real time, eight small surface-emitting lasers embedded in the headset fire harmless near-infrared rays into the brain and the headset’s photodiode sensors convert the reflected light into electrical signals, which are relayed to the controller.
The real-time brain data can either be stored in Flash memory or sent via wifi to a computer for instant analysis and display. A single computer can support up to 24 mind readers at a time, allowing multiple users to monitor brain activity while communicating or engaging in group activities.
In addition to health and medical applications, Hitachi foresees uses for the personal mind reader in fields such as psychology, education and marketing. Although it is unclear what neuromarketing applications the company has in mind, it is pretty clear that access to real-time customer brain data would provide marketers with a better understanding of how and why shoppers make their purchasing decisions. One can also imagine interactive campaigns that, for example, ask customers to think positive thoughts about a certain product in exchange for discount coupons or the chance to win a prize.
The technology could also be used in new forms of entertainment such as “mind gaming,” where the player’s physical brain activity becomes a part of game play. It is also feasible to integrate the brain scanner with a remote control brain-machine interface that would allow users to operate electronic devices with their minds.
Hitachi has yet to determine when the personal mind reader will be made commercially available.
Hitachi has successfully tested a brain-machine interface that allows users to turn power switches on and off with their mind. Relying on optical topography, a neuroimaging technique that uses near-infrared light to map blood concentration in the brain, the system can recognize the changes in brain blood flow associated with mental activity and translate those changes into voltage signals for controlling external devices. In the experiments, test subjects were able to activate the power switch of a model train by performing mental arithmetic and reciting items from memory.
The prototype brain-machine interface allows only simple control of switches, but with a better understanding of the subtle variations in blood concentrations associated with various brain activities, the signals can be refined and used to control more complex mechanical operations.
In the long term, brain-machine interface technology may help paralyzed patients become independent by empowering them to carry out actions with their minds. In the short term, Hitachi sees potential applications for this brain-machine interface in the field of cognitive rehabilitation, where it can be used as an entertaining tool for demonstrating a patient’s progress.
The company hopes to make this technology commercially available in five years.
A University of Electro-Communications team of researchers led by professor Kazuo Tanaka has developed a prototype of an electric wheelchair that the user can steer simply by thinking of which direction he or she would like to go.
The wheelchair interprets the user’s intended direction by means of a skull cap outfitted with a system of sensors. The sensors read the brain waves, enabling the user to control the wheelchair’s direction simply by thinking “move left” or “move right.” Tests have shown that the wheelchair has an 80% degree of accuracy in interpreting the user’s intentions and moving in the desired direction.
The field of mind-controlled technology has seen a number of significant developments recently, and the promise of wheelchairs, televisions and other devices that can be controlled by people with physical disabilities looms on the horizon.
The developers of the wheelchair also envision applications in computer games and in the field of entertainment.
The idea of using a brain interface in entertainment reminds me of this video excerpt from the “Music for Solo Performer,” a sound piece composed by Alvin Lucier in 1964. In this performance, EEG electrodes attached to the performer’s scalp pick up brain waves, which are used to control a variety of percussion instruments. The resulting music has a nice, mind-altering effect.
“Brain! - Exploring Wondrous Mysteries,” an exhibit showcasing the latest in brain research, has opened at the National Museum of Emerging Science and Technology (Miraikan) in Odaiba, Tokyo.
Featured is a collection of about 150 brains and nervous systems of animals ranging from whales to insects (and humans). The exhibit is divided into three areas designed to give visitors a well-rounded tour of the mysteries of the brain. One area focuses on the brain’s functions and evolution, another area includes interactive exhibits that provide a deeper understanding of how the five senses work, and another introduces a variety of technology used in neuroscience research.
The entrance fee is 900 yen for adults and 350 yen for visitors under 18. The exhibit runs through May 31.
Researchers at Osaka University are stepping up efforts to develop robotic body parts controlled by thought, by placing electrode sheets directly on the surface of the brain. Led by Osaka University Medical School neurosurgery professor Toshiki Yoshimine, the research marks Japan’s first foray into invasive (i.e. requiring open-skull surgery) brain-machine interface research on human test subjects. The aim of the research is to develop real-time mind-controlled robotic limbs for the disabled, according to an announcement made at an April 16 symposium in Aichi prefecture. 
In an effort to accelerate the development of next-generation automobiles and robots, Toyota is turning to some of Japan’s top neuroscientists. According to a December 14 announcement, the automaker has teamed up with the Institute of Physical and Chemical Research (
A team of University of Tokyo researchers led by professors Hitoshi Sakano and Ko Kobayakawa have announced they have genetically engineered a mouse that does not fear cats, simply by controlling its sense of smell. By tweaking genes to disable certain functions of the 
Hitachi has successfully tested a brain-machine interface that allows users to turn power switches on and off with their mind. Relying on 
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